| DC47407 |
Antimalarial agent 3
|
Antimalarial agent 3 shows nanomolar antiplasmodial activity (IC50 = 0.035 μM) and has a very high selectivity index with respect to mammalian cells. |
| DC47406 |
Antileishmanial agent-2
|
Antileishmanial agent-2 shows submicromolar antileishmanial activity (IC50 = 0.29 μM) and a very high selectivity index with respect to mammalian cells. |
| DC47405 |
Antimalarial agent 2
|
Antimalarial agent 2 is a novel orally efficacious antimalarials that suggests a fast in vitro killing profile. |
| DC47404 |
TCMDC-125431
|
TCMDC-125431 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization. |
| DC47403 |
TCMDC-136230
|
TCMDC-136230 is a novel disruptor of the malaria parasite calcium dynamics but minimally inhibits heme crystallization. |
| DC47402 |
TCMDC-125457
|
TCMDC-125457 is potent in inducing calcium redistribution but minimally inhibits heme crystallization. TCMDC-125457 demonstrated high efficacy when pulsed in a single-dose combination with artesunate against tightly synchronized artemisinin-resistant ring-stage parasites. |
| DC47401 |
Antileishmanial agent-1
|
Antileishmanial agent-1 exhibits the activity against L. amazonensis promastigotes (IC50 = 15.52 μM) and intracellular amastigotes (IC50 = 4.10 μM). |
| DC47400 |
BRD5018
|
BRD5018 is an antimalarial agent. |
| DC47397 |
Carpaine
|
Carpaine is an alkaloid isolated from Carica papaya Linn with anti-thrombocytopenic activity, exhibits potent activity in sustaining platelet counts with no acute toxicity. Carpaine has anti-plasmodial activity to prevent malaria. |
| DC47107 |
14-Deoxy-11-oxoandrographolide
|
14-Deoxy-11-oxoandrographolide is an antileishmanial agent. 14-Deoxy-11-oxoandrographolide inhibits the replication of heal chikungunya virus (CHIKV) and can be used for CHIKV infection research. |
