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1alpha, 24, 25-Trihydroxy VD2

  Cat. No.:  DC42475  
Chemical Structure
457048-34-9
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More than 5000 active chemicals with high quality for research!
Field of application
1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 457048-34-9
Chemical Name: 1alpha, 24, 25-Trihydroxy VD2
SMILES: O[C@@H](C[C@H](O)C/1=C)CC1=C\C=C2[C@@](CC[C@@H]3[C@@H](/C=C/C(O)(C)C(C)(O)C)C)([H])[C@]3(C)CCC\2
Formula: C28H44O4
M.Wt: 444.65
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_26082_DC42475_457048-34-9
COA
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Cat. No. Product name Field of application
DC44029 TEI-9648 TEI-9648, a Vitamin D3 Lactone analogue, is a potent and specific vitamin D receptor (VDR) antagonist. TEI-9648 inhibits VDR/VDRE-mediated genomic actions of 1α,25(OH)2D3. TEI-9648 also inhibits HL-60 cell differentiation induced by of 1α,25(OH)2D3. TEI-9648 has the potential for bone metabolism research.
DC42526 Triciferol Triciferol functions as a multiple ligand with combined VDR agonist and HDAC antagonist activities. Triciferol binds directly to the VDR (IC50=87 nM), and functions as an agonist with 1,25D-like potency on several 1,25D target genes. Triciferol induces marked tubulin hyperacetylation, and augments histone acetylation at concentrations that largely overlap those where VDR agonism is observed. Antiproliferative and cytotoxic activities.
DC42476 5,6-trans-Vitamin D3 5,6-trans-Vitamin D3 (5,6-trans-Cholecalciferol;5,6-trans-Colecalciferol) is a photoproduct of vitamin D3. Vitamin D3 is a naturally occuring form of vitamin D. Vitamin D3 induces cell differentiation and prevents proliferation of cancer cells.
DC42475 1alpha, 24, 25-Trihydroxy VD2 1alpha, 24, 25-Trihydroxy VD2 is a vitamin D analog.
DC28450 ZK168281 ZK168281 is a 25-carboxylic ester 1α,25(OH)2D3 analog and a pure VDR antagonist with a Kd value of 0.1 nM. ZK168281 is an effective inhibitor of the coactivator (CoA) interaction of its receptor.
DC28449 TEI-9647 TEI-9647 is a first and potent VDR/vitamin D-responsive element (DRE)-mediated genomic actions antagonist. TEI-9647 is a 1α,25-dihydroxyvitamin D3-26,23-lactone (1α,25-lactone) analogue.
DC28448 ZK159222 ZK159222, a 25-carboxylic ester analogue of 1α,25-(OH)2D3, is a potent 1α,25-(OH)2D3 receptor (VDR) agonist. The mechanism of ZK159222 antagonistic action is mediated by a lack of ligand-induced vitamin D receptor interaction with coactivators. ZK159222 has a partial agonistic character.
DC28071 CB1151 CB1151 is a 20-epi analogue of 1,25 dihydroxyvitamin D3 (VD) with potent anti-tumor effects. CB1151 inhibits MCF-7 cell growth with an IC50 value of 0.82 nM.
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