AT-511(Bemnifosbuvir free base)

  Cat. No.:  DC39023   Featured
Chemical Structure
1998705-64-8
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More than 5000 active chemicals with high quality for research!
Field of application
AT-511, the free base form of AT-527, against several coronaviruses, including SARS-CoV-2, the causative agent of COVID-19. In normal human airway epithelial (HAE) cell preparations, the average concentration of AT-511 required to inhibit replication of S
Cas No.: 1998705-64-8
Chemical Name: Bemnifosbuvir
Synonyms: Propan-2-yl (2S)-2-[[[(2R,3R,4R)-5-[2-amino-6-(methylamino)purin-9-yl]-4-fluoro-3-hydroxy-4-methylox;AT-511;Bemnifosbuvir
SMILES: P(N[C@H](C(=O)OC(C)C)C)(=O)(OC1C=CC=CC=1)OC[C@@H]1[C@H]([C@](C)(C(N2C=NC3C(NC)=NC(N)=NC2=3)O1)F)O
Formula: C24H33FN7O7P
M.Wt: 581.533689260483
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: AT-511 is a novel phosphoramidate prodrug of 2'-fluoro-2'-C-methylguanosine-5'-monophosphate that has potent in vitro activity against HCV. The EC50 of AT-511, determined using HCV laboratory strains and clinical isolates with genotypes 1-5, ranged from 5
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Cat. No. Product name Field of application
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