Description: |
A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM For rat and human receptors respectively). A-740003 displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. A-740003 reduces nociception in animal models of persistent neuropathic and inflammatory pain.
For the detailed information of A-740003, the solubility of A-740003 in water, the solubility of A-740003 in DMSO, the solubility of A-740003 in PBS buffer, the animal experiment (test) of A-740003, the cell expriment (test) of A-740003, the in vivo, in vitro and clinical trial test of A-740003, the EC50, IC50,and Affinity of A-740003, Please contact DC Chemicals. |