A-740003

  Cat. No.:  DC7351  
Chemical Structure
861393-28-4
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More than 5000 active chemicals with high quality for research!
Field of application
A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively).
Cas No.: 861393-28-4
Chemical Name: N-[1-[(E)-[(cyanoamino)-(quinolin-5-ylamino)methylidene]amino]-2,2-dimethylpropyl]-2-(3,4-dimethoxyphenyl)acetamide
Synonyms: A 740003; A740003
SMILES: N#C/N=C(NC(NC(CC1=CC(OC)=C(C=C1)OC)=O)C(C)(C)C)NC2=CC=CC3=NC=CC=C23
Formula: C26H30N6O3
M.Wt: 474.57
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM For rat and human receptors respectively). A-740003 displays selectivity over a variety of P2X and P2Y receptors up to a concentration of 100 μM. A-740003 reduces nociception in animal models of persistent neuropathic and inflammatory pain. For the detailed information of A-740003, the solubility of A-740003 in water, the solubility of A-740003 in DMSO, the solubility of A-740003 in PBS buffer, the animal experiment (test) of A-740003, the cell expriment (test) of A-740003, the in vivo, in vitro and clinical trial test of A-740003, the EC50, IC50,and Affinity of A-740003, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC7351 A-740003 A-740003 is potent, selective and competitive P2X7 receptor antagonist (IC50 values are 18 and 40 nM for rat and human receptors respectively).
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