Ac-LETD-AFC|CAS 210345-02-1|DC Chemicals

Cas No.:	210345-02-1
Chemical Name:	N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl-L-α-asparagine
Synonyms:	L-a-Asparagine, N-acetyl-L-leucyl-L-a-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-(9CI);N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asp;4-[(2-acetamido-4-methylpentanoyl)amino]-5-[[1-[[3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid;Ac-LETD-AFC;AC-LEU-GLU-THR-ASP-AFC;N-Acetyl-L-leucyl-L-α-glutamyl-L-threonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-L-α-asparagine;Ac-Leu-Glu-Thr-Asp-7-Amino-4-trifluoromethylcoumarin;Ac-LGlutD-AFC;AFC157;N-Acetylleucyl-alpha-glutamylthreonyl-N-[2-oxo-4-(trifluoromethyl)-2H-1-benzopyran-7-yl]-alpha-asparagine;CS-0136725;210345-02-1;(4S,7S,10S,13S)-7-(2-carboxyethyl)-10-((R)-1-hydroxyethyl)-4-isobutyl-2,5,8,11-tetraoxo-13-(2-oxo-4-(trifluoromethyl)-2H-chromen-7-ylcarbamoyl)-3,6,9,12-tetraazapentadecan-15-oic acid;(4S)-4-[[(2S)-2-acetamido-4-methylpentanoyl]amino]-5-[[(2S,3R)-1-[[(2S)-3-carboxy-1-oxo-1-[[2-oxo-4-(trifluoromethyl)chromen-7-yl]amino]propan-2-yl]amino]-3-hydroxy-1-oxobutan-2-yl]amino]-5-oxopentanoic acid;AKOS040755204;HY-P2620;DA-60773
SMILES:	FC(C1=C([H])C(=O)OC2=C1C([H])=C([H])C(=C2[H])N([H])C(C([H])(C([H])([H])C(=O)O[H])N([H])C(C([H])(C([H])(C([H])([H])[H])O[H])N([H])C(C([H])(C([H])([H])C([H])([H])C(=O)O[H])N([H])C(C([H])(C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])N([H])C(C([H])([H])[H])=O)=O)=O)=O)=O)(F)F
Formula:	C₃₁H₃₈F₃N₅O₁₂
M.Wt:	729.6549
Purity:	98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

MSDS

Cat. No.	Product name	Field of application
DC60824	Ac-LETD-AFC	Ac-LETD-AFC is a caspase-8 fluorogenic substrate. Ac-LETD-AFC can measure caspase-8 fluorogenic activity and can be used for the research of cancer cell apoptosis and oxidative stress metabolism.
DC60823	Ac-ATAD-AFC(Caspase-12 Substrate)	Ac-ATAD-AFC(Caspase-12 Substrate) is a fluorogenic substrate for caspase-12.
DC67293	D-Val-Gly-Arg-pNA	D-Val-Gly-Arg-p-nitroaniline (D-VGR-pNA) is a synthetic chromogenic peptide substrate specifically designed for assessing the enzymatic activity of tissue plasminogen activator (tPA), including its isoforms tPA I and tPA II. Upon cleavage by tPA, the release of p-nitroaniline (pNA) generates a measurable colorimetric signal, enabling precise quantification of amidolytic activity. This substrate is widely utilized in biochemical assays to study tPA’s role in fibrinolysis and to evaluate its enzymatic kinetics in both research and diagnostic applications.
DC60339	Cephalofurimazine (CFz)	Cephalofurimazine (CFz) is a NanoLuc substrate optimized for enhanced brain performance. When paired with Antares luciferase, it generates over 20 times more signal from the brain compared to the traditional combination of D-luciferin and firefly luciferase.
DC82050	Coelenterazine H	Coelenterazine h, a modified form of Coelenterazine, exhibits heightened sensitivity to Ca2+ compared to the native compound, making it an effective tool for detecting subtle fluctuations in Ca2+ concentrations.
DC74576	Fluorofurimazine	Fluorofurimazine is an advanced furimazine derivative with enhanced aqueous solubility, allowing for greater signal output compared to furimazine in bioluminescence imaging. This compound supports higher substrate concentrations and delivers improved sensitivity for in vivo optical imaging applications.
DCC5420	Viviren	ViviRen is a synthetic analog of coelenterazine specifically designed for bioluminescence imaging (BLI), offering enhanced performance in visualizing biological processes.
DCC1510	Coelenterazine E	Coelenterazine E serves as a bioluminescent probe, widely utilized for its ability to emit light in biological and chemical applications.
DC72431	For-Met-Leu-pNA（N-formylated peptide substrate)	For-Met-Leu-pNA is an N-formylated peptide substrate specifically designed for use in deformylase activity assays, providing a reliable tool for studying enzyme function.
DC72410	Ac-Phe-Gly-pNA(chymotrypsin substrate)	Ac-Phe-Gly-pNA is a synthetic peptide substrate specifically tailored for detecting chymotrypsin activity, offering high specificity for this enzyme.