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Angstrom6

  Cat. No.:  DC42471  
Chemical Structure
220334-14-5
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Field of application
Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the uPA/uPAR cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling.
Cas No.: 220334-14-5
Chemical Name: Angstrom6
Synonyms: Ac-Lys-Pro-Ser-Ser-Pro-Pro-Glu-Glu-NH2
Formula: C39H62N10O15
M.Wt: 910.97
MSDS
TITLE DOWNLOAD
MSDS_26078_DC42471_220334-14-5
COA
LOT NO. DOWNLOAD
Cat. No. Product name Field of application
DC47408 28-O-β-D-Glucopyranosyl pomolic acid 28-O-β-D-Glucopyranosyl pomolic acid is a urokinase plasminogen activator inhibitor with IC50 at 37.82 μM.
DC46325 Diaplasinin Diaplasinin (PAI-749) is a plasminogen activator inhibitor-1 (PAI-1) inhibitor with IC50 of 295 nm. Antithrombotic efficacy.
DC45370 UK122 UK122 is a potent and selective urokinase-type plasminogen activator (uPA) inhibitor with an IC50 of 0.2 μM. UK122 shows no or little inhibition of tissue-type PA (tPA), plasmin, thrombin, and trypsin (all IC50>100 μM). UK122, 4-oxazolidinone analogue, is an anticancer agent and inhibits cancer cell migration and invasion.
DC42471 Angstrom6 Angstrom6 (A6 Peptide) is an 8 amino-acid peptide derived from single-chain urokinase plasminogen activator (scuPA) and interferes with the uPA/uPAR cascade and abrogates downstream effects. Angstrom6 binds to CD44 resulting in the inhibition of migration, invasion, and metastasis of tumor cells, and the modulation of CD44-mediated cell signaling.
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