Avasimibe

Cas No.:	166518-60-1
Chemical Name:	Avasimibe
Synonyms:	2,6-Diisopropylphenyl (2-(2,4,6-triisopropylphenyl)acetyl)sulfamate;N-(2,6-Dipropan-2-ylphenoxy)sulfonyl-2-(2,4,6-tripropan-2-ylphenyl)acetamide;Avasimibe;[[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid;2,6-Diisopropylphenyl (2-(2,4,6-triisopropylphenyl)-acetyl)sulfamate;AVASIMIBE(CI-1011);[2,6-di(propan-2-yl)phenyl] N-[2-[2,4,6-tri(propan-2-yl)phenyl]acetyl]sulfamate;CI1011;CI-1011;PD148515;PD-148515;Avasimibe Solution, 100ppm;2,6-diisopropylphenyl 2-(2,4,6-triisopropylphenyl)acetylsulfamate;N-[(2,6-DIISOPROPYLPHENOXY)SULFONYL]-2-(2,4,6-TRIISOPROPYLPHENYL)ACETAMIDE;((2,4,6-TRIS(1-METHYLETHYL)PHENYL)ACETYL)SULFAMICACID2,6-BIS(1-METHYLETHYL)PHENYLESTER;CI-1011; PD 148515; [[2,4,6-tris(1-methylethyl)phenyl]acetyl]-, 2,6-bis(1-methylethyl)phenyl ester] sulfamic acid;Avasimibe, >=98%;CI 1011;PD 148515;28LQ20T5RC;2,6-Diisopropylphenyl ((2,4,6-triisopropylphenyl)acetyl)sulfamate;((2,4,6-Tris(1-methylethyl)phenyl)acetyl)sulfamic acid 2,6-bis(1-methylethyl)phenyl ester;N
SMILES:	c1(C(C)C)cc(cc(c1CC(NS(Oc1c(cccc1C(C)C)C(C)C)(=O)=O)=O)C(C)C)C(C)C
Formula:	C29H43NO4S
M.Wt:	501.721
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Avasimibe is an oral inhibitor of acyl-Coenzyme A:cholesterol acyltransferase (ACAT) with IC50s of 24 and 9.2 µM for ACAT1 and ACAT2, respectively.