BMVC-8C3O

Cas No.:	1301708-12-2
Chemical Name:	Bmvc-8C3O
Synonyms:	BMVC-8C3O
SMILES:	[I-].[I-].[I-].O(C([H])([H])C([H])([H])OC([H])([H])C([H])([H])OC([H])([H])C([H])([H])N1C2C([H])=C([H])C(/C(/[H])=C(\[H])/C3C([H])=C([H])[N+](C([H])([H])[H])=C([H])C=3[H])=C([H])C=2C2C([H])=C(/C(/[H])=C(\[H])/C3C([H])=C([H])[N+](C([H])([H])[H])=C([H])C=3[H])C([H])=C([H])C1=2)C([H])([H])C([H])([H])[N+]1(C([H])([H])[H])C([H])([H])C([H])([H])C([H])([H])C([H])([H])C1([H])[H]
Formula:	C42H53I3N4O3
M.Wt:	1042.6086
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:	BMVC-8C3O is a DNA G-quadruplexe (G4) ligand which can induce topological conversion of non-parallel to parallel forms in human telomeric DNA G4s[1].
In Vitro:	BMVC-8C3O induces topological conversion of Tel23 from a hybrid-I G4 to a parallel G4 in K+solution[1]. BMVC-8C3O binding can induce topological changes of different non-parallel human telomeric G4s into the same parallel topology[1].
References:	[1]. Wang ZF, et al. A novel transition pathway of ligand-induced topological conversion from hybrid forms to parallel forms of human telomeric G-quadruplexes. Nucleic Acids Res. 2016 May 5;44(8):3958-68.