BRD7116
Cat. No.: DC8446
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Chemical Structure
329059-55-4
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Field of application
BRD7116 competitively binds to bacterial DNA gyrase, exhibits an EC50 of 200 nM for LSCe cells, with cell-non-autonomous anti-leukemia activity.
Cas No.: |
329059-55-4 |
Chemical Name: |
BRD 7116 |
Synonyms: |
BRD 7116;BRD-7116;2,2,3,3-Tetramethyl-N-[4-[4-[(2,2,3,3-tetramethylcyclopropanecarbonyl)amino]phenyl]sulfonylphenyl]cyclopropane-1-carboxamide;BRD7116 |
SMILES: |
O=S(C1=CC=C(NC(C2C(C)(C)C2(C)C)=O)C=C1)(C3=CC=C(NC(C4C(C)(C)C4(C)C)=O)C=C3)=O |
Formula: |
C28H36N2O4S |
M.Wt: |
496.66144657135 |
Purity: |
>98% |
Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: |
BRD7116 competitively binds to bacterial DNA gyrase, exhibits an EC50 of 200 nM for LSCe cells, with cell-non-autonomous anti-leukemia activity. |
References: |
[1]. Hartwell KA, et al. Niche-based screening identifies small-molecule inhibitors of leukemia stem cells. Nat Chem Biol. 2013 Dec;9(12):840-848 |
MSDS
COA
LOT NO. |
DOWNLOAD |
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2018-0101 |
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2018-0101 |
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