Cas No.: | 957217-65-1 |
Chemical Name: | 2-(2-methyl-1,4-dioxa-8-azaspiro[4.5]decan-8-yl)-8-nitro-6-(trifluoromethyl)-4H-benzo[e][1,3]thiazin-4-one |
Synonyms: | BTZ043 Racemic; BTZ043 Racemate; BTZ043; BTZ 043; BTZ-043. |
SMILES: | O=C1N=C(N(CC2)CCC32OCC(C)O3)SC4=C([N+]([O-])=O)C=C(C(F)(F)F)C=C14 |
Formula: | C17H16F3N3O5S |
M.Wt: | 431.3862 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | BTZ043 Racemate is the racemate of BTZ043, BTZ043 is an inhibitor of decaprenyl-phosphoribose-epimerase (DprE1), and the antimicrobial activity of BTZ043 is more potent than BTZ043 Racemate. |
Target: | DprE1[1]. |
References: | [1]. Gao C, et al. Synthesis and structure-activity relationships evaluation of benzothiazinone derivatives as potential anti-tubercular agents. Bioorg Med Chem Lett. 2013 Sep 1;23(17):4919-22. |