Cas No.: | 1159600-41-5 |
Chemical Name: | Basmisanil |
Synonyms: | Basmisanil;RG1662;RO5186582;(1,1-Dioxo-4-thiomorpholinyl)[6-[[3-(4-fluorophenyl)-5-methylisoxazol-4-yl]methoxy]pyridin-3-yl]methanone;RG 1662;788PET5SUA;(1,1-Dioxidothiomorpholino)(6-((3-(4-fluorophenyl)-5-methylisoxazol-4-yl)methoxy)pyridin-3-yl)methanone;Basmisanil [INN];(1,1-dioxo-1,4-thiazinan-4-yl)-[6-[[3-(4-fluorophenyl)-5-methyl-1,2-oxazol-4-yl]methoxy]pyridin-3-yl]methanone;Basmisanil [USAN:INN];Basmisani;Basmisanil(RG1662);Basmisanil (USAN/INN);GTPL10427;VCGRFBXVSFAGGA-UHFFFAOYSA-N;BDBM133427;BCP19013 |
SMILES: | S1(C([H])([H])C([H])([H])N(C(C2=C([H])N=C(C([H])=C2[H])OC([H])([H])C2=C(C([H])([H])[H])ON=C2C2C([H])=C([H])C(=C([H])C=2[H])F)=O)C([H])([H])C1([H])[H])(=O)=O |
Formula: | C21H20FN3O5S |
M.Wt: | 445.4640 |
Purity: | >98% |
Sotrage: | 4°C for 1 year, -20°C for more than 2 years |
Description: | Basmisanil is a highly selective GABAAα5 negative allosteric modulator. |
References: | [1]. Myers JF, et al. Quantification of [11C]Ro15-4513 GABAAα5 specific binding and regional selectivity in humans. J Cereb Blood Flow Metab. 2016 Jul 27. |