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Bexarotene

  Cat. No.:  DCAPI1078   Featured
Chemical Structure
153559-49-0
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More than 5000 active chemicals with high quality for research!
Field of application
Bexarotene (LGD1069) is a high-affinity and selective retinoid X receptors (RXR) agonist with EC50s of 33, 24, 25 nM for RXRα, RXRβ, and RXRγ, respectively. Bexarotene shows limited affinity for RAR receptors (EC50 >10000 nM)[1][2][3]. Bexarotene can be used for the research of cutaneous T-cell lymphoma.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 153559-49-0
Chemical Name: Bexarotene
Synonyms: Bexarotene;4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]benzoic acid;Targretin;4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)vinyl)benzoic acid;Bexaroten;Lg 1069;LG 69;LGD1069;Targret;Targretyn;LGD-1069;SR-11247;Lg100069;SR 11247;Hsdb 7453;Targrexin;LGD 1069;bexarotenum;p-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl)benzoic acid;4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl]benzoic acid;LG 100069;A61RXM4375;4-[1-(3,5,5,8,8-pentamethyl-6,7-dihydronaphthalen-2-yl)ethenyl]benzoic acid;4-(1-(5,6,7,8-Tetrahydro-3,5,5,8,;Bexarotene(LGD-1069);4-(1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic acid;Tox21_302407;4-(1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl)benzoic acid;166175-31-1;4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)vinyl]benzoic acid;AB01275475_02;NS00000606;SR-05000001480;AB01275475-01;NCGC00181016-04;MLS006010146;SS-4628;4-[1-(3,5,5,8,8-pentamethyltetralin-2-yl)ethenyl]benzoic acid;4-(1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl)benzoic acid;NAVMQTYZDKMPEU-UHFFFAOYSA-N;BEXAROTENE [VANDF];L01XX25;HMS3655D19;NSC-783322;Benzoic acid, 4-(1-(5,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)-;BEXAROTENE [HSDB];SW203810-3;BEXAROTENE [ORANGE BOOK];NCGC00181016-03;BEXAROTENE [MI];AMY24869;4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-2-naphthyl)ethenyl]benzoic acid;NCGC00181016-02;Benzoic acid,6,7,8-tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl]-;NSC-747528;NSC747528;Bexarotene [USAN:INN:BAN];HMS2089L14;DB00307;CHEBI:50859;FT-0657110;4-[1-(5,6,7,8,-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphtalenyl)ethenyl]benzoic acid;NSC 747528;J-519847;s2098;3-methyl-TTNEB;Bexarotene [USAN];CAS-153559-49-0;BEXAROTENE [INN];MFCD00932428;BCP9000396;Bexarotene, >=98% (HPLC);NCGC00181016-20;Tox21_112666_1;SR-05000001480-2;CHEMBL1023;BEXAROTENE [WHO-DD];LG-100069;Bexarotene oral(targretin);4,6-DICHLORO-2,3-DIHYDRO-1H-INDOLEHYDROCHLORIDE;bexaroteno;4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthalenyl)ethenyl)benzoic Acid;B4798;EN300-19769221;Tox21_112666;SR-05000001480-1;Q418192;NSC783322;UNII-A61RXM4375;3-methyl TTNEB;SCHEMBL9025;DTXSID1040619;4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydro-naphthalen-2-yl)-vinyl]-benzoic acid;Ro 26-4455;4-(1-(3,5,5,8,8-Pentamethyl-5,6,7,8-tetrahydronaphthalen-2-yl)ethenyl)benzoic acid;HMS3747C21;NSC 741061;4k6i;GTPL2807;CCG-221823;BB164246;SMR001614557;BCP04099;Bexarotene (JAN/USAN/INN);HY-14171;A809441;NCGC00181016-01;BRD-K92441787-001-02-5;BCP0726000106;DTXCID9020619;BIDD:PXR0021;HMS3884B07;4-[1-(3,5,5,8,8-Pentamethyl-2-5,8-dihydronaphthyl)vinyl]benzoic acid;SB17341;Targretin (TN);BEXAROTENE (MART.);BEXAROTENE [JAN];NCGC00255426-01;153559-49-0;CS-0626;AC-24569;NCGC00181016-08;4-[1-(3,5,5,8,8-pentamethyl-5,6,7,8-tetrahydr...
SMILES: O([H])C(C1C([H])=C([H])C(=C([H])C=1[H])C(=C([H])[H])C1C(C([H])([H])[H])=C([H])C2=C(C=1[H])C(C([H])([H])[H])(C([H])([H])[H])C([H])([H])C([H])([H])C2(C([H])([H])[H])C([H])([H])[H])=O
Formula: C24H28O2
M.Wt: 348.4779
Purity: >99%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: For the detailed information of Bexarotene, the solubility of Bexarotene in water, the solubility of Bexarotene in DMSO, the solubility of Bexarotene in PBS buffer, the animal experiment（test） (test) of Bexarotene, the cell expriment (test) of Bexarotene, the in vivo, in vitro and clinical trial test of Bexarotene, the EC50, IC50,and Affinity of Bexarotene,, please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
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