CBR-470-1

  Cat. No.:  DC40756   Featured
Chemical Structure
2416095-06-0
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Field of application
CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.
Cas No.: 2416095-06-0
Chemical Name: Schembl21033073
Synonyms: (3R,4S)-3-((4-Chlorophenyl)sulfonyl)-4-(isobutylamino)tetrahydrothiophene 1,1-dioxide;rel-(3R,4S)-3-((4-Chlorophenyl)sulfonyl)-4-(isobutylamino)tetrahydrothiophene 1,1-dioxide;(3R,4S)-3-[(4-chlorophenyl)sulfonyl]-4-(isobutylamino)tetrahydro-1H-1lambda-thiophene-1,1-dione;Schembl21033073;CBR-470-1
SMILES: ClC1C([H])=C([H])C(=C([H])C=1[H])S([C@@]1([H])C([H])([H])S(C([H])([H])[C@]1([H])N([H])C([H])([H])C([H])(C([H])([H])[H])C([H])([H])[H])(=O)=O)(=O)=O
Formula: C14H20ClNO4S2
M.Wt: 365.8959
Purity: >98%
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
Description: CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.
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MSDS_23769_DC40756_2416095-06-0
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Cat. No. Product name Field of application
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DC40756 CBR-470-1 CBR-470-1 is an inhibitor of the glycolytic enzyme phosphoglycerate kinase 1 (PGK1). CBR-470-1 is also a non-covalent Nrf2 activator. CBR-470-1 protects SH-SY5Y neuronal cells against MPP+-induced cytotoxicity through activation of the Keap1-Nrf2 cascade.
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