CX6258

  Cat. No.:  DC7153   Featured
Chemical Structure
1202916-90-2
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More than 5000 active chemicals with high quality for research!
Field of application
CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity.
Cas No.: 1202916-90-2
Chemical Name: 2H-indol-2-one 5-chloro-3-[[5-[3-[(hexahydro-4-methyl-1h-14-diazepin-1-yl)carbonyl]phenyl]-2-furanyl]methylene]-1,3-dihydro- (3e)-
Synonyms: 2H-indol-2-one 5-chloro-3-[[5-[3-[(hexahydro-4-methyl-1h-14-diazepin-1-yl)carbonyl]phenyl]-2-furanyl]methylene]-1,3-dihydro- (3e)-;CX6258;(3E)-5-Chloro-3-[[5-[3-[(hexahydro-4-methyl-1H-1,4-diazepin-1-yl)carbonyl]phenyl]-2-furanyl]methylene]-1,3-dihydro-2H-indol-2-one;(3E)-5-Chloro-3-[(5-{3-[(4-methyl-1,4-diazepan-1-yl)carbonyl]phen yl}-2-furyl)methylene]-1,3-dihydro-2H-indol-2-one;(Z)-5-CHLORO-3-((5-(3-(4-METHYL-1,4-DIAZEPANE-1-CARBONYL)PHENYL)FURAN-2-YL)METHYLENE)INDOLIN-2-ONE.HCL;CX-6258;CX-6258 HCl
SMILES: O=C1NC2=CC=C(Cl)C=C2/C1=C\C3=CC=C(C4=CC=CC(C(N5CCCN(C)CC5)=O)=C4)O3
Formula: C26H24N3O3Cl
M.Wt: 461.94006
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC10047 PIM-447 dihydrochloride PIM447 is novel pan-PIM kinase inhibitor, including Moloney Murine Leukemia (PIM) 1, 2, and 3 Kinase.
DC7153 CX6258 CX-6258 is a potent, orally efficacious Pim 1/2/3 kinase(IC50=5 nM/25 nM/16 nM) inhibitor with excellent biochemical potency and kinase selectivity.
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