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CY5 NHS ester

  Cat. No.:  DC33855   Featured
Chemical Structure
1032678-42-4
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Field of application
This Cyanine5 NHS ester, also known as Cy5 NHS ester, is a reactive dye for the labeling of amino-groups in peptides, proteins, and oligonucleotides. This dye requires a small amount of organic co-solvent to be used in labeling reactions. This reagent is ideal for very cost-efficient labeling of soluble proteins as well as all kinds of peptides and oligonucleotides. This reagent also works well in organic solvents for small molecule labeling.
Cas No.: 1032678-42-4
Chemical Name: Cyanine5 NHS ester
Synonyms: 2-[5-(1,3-Dihydro-1,3,3-trimethyl-2H-indol-2-ylidene)-1,3-pentadien-1-yl]-1-[6-[(2,5-dioxo-1-pyrrolidinyl)oxy]-6-oxohexyl]-3,3-dimethyl-3H-indolium chloride (1:1);Lumiprobe Cy 5 NHS ester;Lumiprobe NHS-Cy5;Cyanine5 NHS ester chloride
SMILES: C12C([N+](CCCCCC(ON3C(=O)CCC3=O)=O)=C(/C=C/C=C/C=C3\C(C)(C)C4=CC=CC=C4N\3C)C1(C)C)=CC=CC=2.[Cl-]
Formula: C36H42ClN3O4
M.Wt: 616.19
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Cyanine5 NHS ester chloride is a red emitting fluorescent dye for labeling of amino-groups in peptides, proteins, and oligonucleotides[1].
References: [1]. Brugada-Vilà P, et al. Oligopeptide-modified poly(beta-amino ester)s-coated AdNuPARmE1A: Boosting the efficacy of intravenously administered therapeutic adenoviruses. Theranostics. 2020;10(6):2744-2758. Published 2020 Feb 3.
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