Cariporide

  Cat. No.:  DC7990  
Chemical Structure
159138-80-4
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Field of application
Cariporide is a selective Na+/H+ exchanger isoform 1 (NHE1) inhibitor (IC50 values are 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2 respectively).
Cas No.: 159138-80-4
Chemical Name: N-(Diaminomethylene)-4-isopropyl-3-(methylsulfonyl)benzamide
SMILES: CS(C1=CC(C(/N=C(N)/N)=O)=CC=C1C(C)C)(=O)=O
Formula: C12H17N3O3S
M.Wt: 283.35
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Cariporide is a NHE-1 (sodium-hydrogen exchanger isoform-1) inhibitor. Rat studies indicate that cariporide blocks apoptosis of cardiac muscle cells. Additional studies show that the compound interacts with and weakens mitochondrial Ca2+ overload and the permeability transition pore (PTP). For the detailed information of Cariporide, the solubility of Cariporide in water, the solubility of Cariporide in DMSO, the solubility of Cariporide in PBS buffer, the animal experiment (test) of Cariporide, the cell expriment (test) of Cariporide, the in vivo, in vitro and clinical trial test of Cariporide, the EC50, IC50,and affinity,of Cariporide, Please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC7990 Cariporide Cariporide is a selective Na+/H+ exchanger isoform 1 (NHE1) inhibitor (IC50 values are 0.05, 3 and 1000 μM for NHE1, NHE3 and NHE2 respectively).
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