| Cas No.: | 83881-52-1 |
| Chemical Name: | 2-[2-[4-[(4-chlorophenyl)-phenylmethyl]piperazin-1-yl]ethoxy]acetic acid;dihydrochloride |
| Synonyms: | Cetirizine Hydrochloride; 83881-52-1; Reactine; Zyrtec; CETIRIZINE HYDROCHLORIDE; Alerlisin; Aliud Brand of Cetirizine Dihydrochloride; Alpharma Brand of Cetirizine Dihydrochloride; AWD.pharma Brand of Cetirizine Dihydrochloride; Azupharma Brand of Cetiri |
| SMILES: | Cl.Cl.OC(COCCN1CCN(C(C2C=CC(Cl)=CC=2)C2C=CC=CC=2)CC1)=O |
| Formula: | C21H27Cl3N2O3 |
| M.Wt: | 461.81 |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Cetirizine 2Hcl, a second-generation antihistamine, is a major metabolite of hydroxyzine, and a racemic selective H1 receptor inverse agonist used in the treatment of allergies, hay fever, angioedema, and urticaria.Cetirizine crosses the blood-brain barrier only slightly, reducing the sedative side-effect common with older antihistamines. It has also been shown to inhibit eosinophil chemotaxis and LTB4 release. At a dosage of 20 mg, Boone et al. found that it inhibited the expression of VCAM-1 in patients with atopic dermatitis. The levorotary enantiomer of cetirizine, known as levocetirizine, is the more active form. From Wikipedia. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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