Ciproxifan (FUB-359)

  Cat. No.:  DC2062   Featured
Chemical Structure
184025-18-1
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Field of application
Ciproxifan is an antagonists of H3-type histamine receptors.
Cas No.: 184025-18-1
Chemical Name: 1H-Indole-2,3-dione, 1-[(3,4-dichlorophenyl)methyl]-
Synonyms: FUB359
SMILES: C1CC1C(=O)C2=CC=C(C=C2)OCCCC3=CN=CN3
Formula: C15H9Cl2NO2
M.Wt: 306.14
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Ciproxifan, Antagonists of H3-type histamine receptors exhibit cognitive-enhancing properties in various memory paradigms as well as evidence of antipsychotic activity in normal animals.Ciproxifan is an extremely potent histamine H3 inverse agonist/antagonist.Ciproxifan produces wakefulness and attentiveness in animal studies, and produced cognitive enhancing effects without prominent stimulant effects at relatively low levels of receptor occupancy, and pronounced wakefulness at higher doses.It has there Fore been proposed as a potential treatment For sleep disorders such as narcolepsy and to improve vigilance in old age, particularly in the treatment of conditions such as Alzheimer's disease.It also potentiated the effects of antipsychotic drugs, and has been suggested as an adjuvant treatment For schizophrenia. For the detailed information about the solubility of Ciproxifan (FUB-359) in water, the solubility of Ciproxifan (FUB-359) in DMSO, the solubility of Ciproxifan (FUB-359) in PBS buffer, the animal experiment(test) of Ciproxifan (FUB-359),the in vivo,in vitro and clinical trial test of Ciproxifan (FUB-359),the cell experiment(test) of Ciproxifan (FUB-359),the IC50, EC50 and Affinity of Ciproxifan (FUB-359), please contact DC Chemicals.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC9175 Fexofenadine Hydrochloride Fexofenadine is a third-generation antihistamine pharmaceutical drug used in the treatment of allergy symptoms, such as hay fever, nasal congestion, and urticaria.
DC2062 Ciproxifan (FUB-359) Ciproxifan is an antagonists of H3-type histamine receptors.
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