| Cas No.: | 50-41-9 |
| Chemical Name: | (Z)-2-(4-(2-chloro-1,2-diphenylvinyl)phenoxy)-N,N-diethylethan-1-amine 2-hydroxypropane-1,2,3-tricarboxylate |
| Synonyms: | Clomiphene-R; Clostilbegyt; MER-41; MER41; MER 41; MRL-41; MRL41; MRL41; NSC-35770; NSC35770; NSC 35770 |
| SMILES: | CCN(CCOC1C=CC(C(=C(C2C=CC=CC=2)Cl)C2C=CC=CC=2)=CC=1)CC.OC(CC(C(=O)O)(O)CC(=O)O)=O |
| Formula: | C32H36ClNO8 |
| M.Wt: | 598.08 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | Clomifene Citrate is a selective estrogen receptor modulator.Clomifene Citrate(CC) acted as an estrogen antagonist regardless of the concentration of E2 added together. In conclusion, CC acts as an estrogen agonist/antagonist via ER alpha in a coexisting estrogen concentration-dependent way whereas it acts as an estrogen antagonist via ER beta whether or not estrogen is present. Clomiphene was effective in increasing pregnancy rate compared to placebo (OR 5.8, 95% CI 1.6 to 21.5) as was clomiphene plus dexamethasone treatment (OR 9.46, 95% CI 5.1 to 17.7) compared to clomiphene alone. A significant improvement in the pregnancy rate was reported for clomiphene plus combined oral contraceptives versus clomiphene alone. No evidence of a difference in effect on pregnancy rate was found with any of the other comparisons. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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