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Coumermycin A1

  Cat. No.:  DC41406  
Chemical Structure
4434-05-3
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More than 5000 active chemicals with high quality for research!
Field of application
Coumermycin A1 is a JAK2 signal activator. Coumermycin A1 inhibits DNA Gyrase which thereby inhibits cell division in bacteria.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 4434-05-3
Chemical Name: Coumermycin A1
SMILES: OC(C1=CC=C(O[C@@H]([C@H](O)[C@H](OC(C2=CC=C(C)N2)=O)[C@H]3OC)OC3(C)C)C(C)=C1O4)=C(NC(C5=CNC(C(NC6=C(O)C7=CC=C(O[C@@H]([C@H](O)[C@H](OC(C8=CC=C(C)N8)=O)[C@H]9OC)OC9(C)C)C(C)=C7OC6=O)=O)=C5C)=O)C4=O
Formula: C55H59N5O20
M.Wt: 1110.08
Sotrage: Please store the product under the recommended conditions in the Certificate of Analysis.
MSDS
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MSDS_24419_DC41406_4434-05-3
COA
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Cat. No. Product name Field of application
DC47591 JAK-IN-14 JAK-IN-14 is a potent and selective JAK1 inhibitor, with an IC50 of <5 μM. JAK-IN-14 is >8-fold more selective for JAK1 than JAK2 and JAK3 (Patent WO2016119700A1, compound 16).
DC47590 Ten01 Ten01 has 5.0 nM activity against JAK1 kinase.
DC47132 JAK1-IN-8 JAK1-IN-8, a potent JAK1 inhibitor (IC50<500 nM), compound 28, extracted from patent WO2016119700A1.
DC47066 Ifidancitinib Ifidancitinib is a potent and selective inhibitor of JAK kinases 1/3. Ifidancitinib can be used in studies of allergies, asthma and autoimmune diseases.
DC47041 Lorpucitinib Lorpucitinib is a Gut-Restricted JAK Inhibitor for the research of Inflammatory Bowel Disease.
DC47039 Itacnosertib Itacnosertib (TP-0184) is both inhibitor to JAK2, ACVR1 (ALK2) and ALK5 as described in WO2014151871.
DC47030 Ilunocitinib Ilunocitinib (compound 27) is a JAK inhibitor (extracted from patent WO2009114512A1).
DC46857 Nezulcitinib Nezulcitinib (TD-0903) is an inhaled and lung-selective pan-Janus kinase (JAK) inhibitor. Nezulcitinib can be used for the research of COVID-19 associated acute lung injury and impaired oxygenation.
DC46856 JAK2/FLT3-IN-1 TFA JAK2/FLT3-IN-1 (TFA) is a potent and orally active dual JAK2/FLT3 inhibitor with IC50 values of 0.7 nM, 4 nM, 26 nM and 39 nM for JAK2, FLT3, JAK1 and JAK3, respectively. JAK2/FLT3-IN-1 (TFA) has anti-cancer activity.
DC46855 Deuruxolitinib Deuruxolitinib (CTP-543), a deuterated Ruxolitinib, modulates the activity of JAK1/JAK2. Deuruxolitinib can be used for the research hair loss disorders (from patent WO2017192905A1, compound I).
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