Cromolyn sodium

Cas No.:	15826-37-6
SMILES:	[Na+].[Na+].OC(COC1=CC=CC2OC(=CC(=O)C1=2)C([O-])=O)COC1=CC=CC2OC(=CC(=O)C1=2)C([O-])=O
Formula:	C23H14Na2O11
M.Wt:	512.33
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Cromolyn sodium is an antiallergic drug.Cromolyn sodium is a chromone complex that acts by inhibiting the release of chemical mediators from sensitized mast cells. It is used in the prophylactic treatment of both allergic and exercise-induced asthma, but does not affect an established asthmatic attack. Pretreatment of IIR mice with Cromolyn sodium prior to ischemia exhibited no changes of ET-1 levels, injury score and inflammation (P>0.05, PreCr vs. M groups). In conclusion, administration of Cromolyn sodium after reperfusion, but not prior to ischemia, attenuates IIRI by downregulating ET-1 and suppressing sustained MC activation . cromolyn sodium has a role in the prevention of Chronic lung disease(CLD). Cromolyn sodium cannot be recommended for the prevention of CLD in preterm infants.