Cyclobenzaprine HCl|cas 6202-23-9|DC Chemicals

Cas No.:	6202-23-9
Chemical Name:	(Z)-3-(10H-dibenzo[a,d][7]annulen-10-ylidene)-N,N-dimethylpropan-1-amine hydrochloride
Synonyms:	Flexeril; Proheptatriene; Lisseril; Proeptatriene; Proheptatrien
SMILES:	Cl.C1C2=C(/C(=C\CCN(C)C)/C3C=CC=CC=3C=C2)C=CC=1
Formula:	C₂₀H₂₂ClN
M.Wt:	311.85
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

Cyclobenzaprine Hcl is a skeletal muscle relaxant and a central nervous system (CNS) depressant.Cyclobenzaprine is a skeletal muscle relaxant and a central nervous system (CNS) depressant. Cyclobenzaprine was thought to be an alpha 2-adrenoceptor agonist that reduced muscle tone by decreasing the activity of descending noradrenergic neurons. Cyclobenzaprine reduced the monosynaptic reflex amplitude dose dependently and this effect was not inhibited by the alpha 2-adrenoceptor antagonists idazoxan and yohimbine. Cyclobenzaprine-induced monosynaptic reflex depression was not attenuated by noradrenergic neuronal lesions produced by 6-hydroxydopamine. Cyclobenzaprine is a 5-HT2 receptor antagonist and that its muscle relaxant effect is due to inhibition of serotonergic, not noradrenergic, descending systems in the spinal cord [1]. The inhibitory effects of cyclobenzaprine on mono- and polysynaptic reflex potentials are due to the inhibition of descending serotonergic systems through 5-HT(2) receptors in the spinal cord [2].

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101
2018-0101

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