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| Cas No.: | 1450666-80-4 |
| Chemical Name: | (4-(5-amino-6-(4-(trifluoromethyl)phenyl)pyrazin-2-yl)phenyl)(piperazin-1-yl)methanone |
| Synonyms: | UCT 943;UCT-943 |
| SMILES: | C(C1=CC=C(C2=NC(C3=CC=C(C(F)(F)F)C=C3)=C(N)N=C2)C=C1)(N1CCNCC1)=O |
| Formula: | C22H20F3N5O |
| M.Wt: | 427.431 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | UCT943 (UCT-943) is a potent, selective, next generation Plasmodium falciparum PI4K inhibitor with IC50 of 23 nM; displays higher asexual blood stage, transmission-blocking, and liver stage activity than MMV048 and is more potent against resistant P. falciparum and P. vivax clinical isolates; demonstrates excellent in vitro antiplasmodial activity in P. berghei and humanized P. falciparum mouse models. |
MSDS
COA
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| 2018-0101 |
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