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| Cas No.: | 120934-96-5 |
| Chemical Name: | 1H-Pyrrole-3-carboxylicacid, 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-, methyl ester |
| Synonyms: | 1H-Pyrrole-3-carboxylicacid, 2,5-dimethyl-4-[2-(phenylmethyl)benzoyl]-, methyl ester;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXYLIC ACID METHYL ESTER;FPL 64176;FPL-64176;FPL-64176 (FPL 64176);methyl 4-(2-benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylate;2,5-Dimethyl-4-[2-(phenylmethyl)benzoyl]-1H-pyrrole-3-carboxlic acid methyl ester;MDMWHKZANMNXTF-UHFFFAOYSA-N;FPL 64176 >94% POTENT CA2+ CHANNEL (;4-(2-Benzylbenzoyl)-2,5-dimethyl-1H-pyrrole-3-carboxylic acid methyl ester;2,5-Dimethyl-4-(2-benzylbenzoyl)-1H-pyrrole-3-carboxylic acid methyl ester;2,5-DIMETHYL-4-[2-(PHENYLMETHYL)BENZOYL]-1H-PYRROLE-3-CARBOXLIC ACID METHYL ESTER |
| SMILES: | COC(C1=C(C)NC(C)=C1C(C1=CC=CC=C1CC1C=CC=CC=1)=O)=O |
| Formula: | C22H21NO3 |
| M.Wt: | 347.407046079636 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | FPL64176 is a potent L-type Ca++ channel activator with EC50 of 16 nM; prolongs action potential duration and enhances contractility in guinea pig papillary muscle, induces contractile response with EC50 of 0.2 uM; produces biexponential tail current decays at -50 mV with fast and slow time constants of 4.30 +/- 0.30 and 44.52 +/- 4.56 msec, respectively; produces large increases in cardiac contractile force and diastolic blood pressure in anesthetized dogs (100 mg/kg, i.v.). |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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