sPLA2-X inhibitor 31

  Cat. No.:  DC10956  
Chemical Structure
2241025-50-1
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Field of application
sPLA2-X inhibitor 31 is a potent, selective secreted phospholipase A2 type X (sPLA2-X) with IC50 of 26 nM, displays 12-fold and 80-fold selectivity over sPLA2-Iia and sPLA2-V, respectively.
Cas No.: 2241025-50-1
Chemical Name: 3-(3-(2-carbamoyl-6-(trifluoromethoxy)-1H-indol-1-yl)phenyl)propanoic acid
SMILES: C(O)(=O)CCC1=CC=CC(N2C3=C(C=CC(OC(F)(F)F)=C3)C=C2C(=O)N)=C1
Formula: C19H15F3N2O4
M.Wt: 392.334
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: sPLA2-X inhibitor 31 is a potent, selective secreted phospholipase A2 type X (sPLA2-X) with IC50 of 26 nM, displays 12-fold and 80-fold selectivity over sPLA2-Iia and sPLA2-V, respectively; demonstrates improved lipolitic activity of sPLA2-X on HDL (IC50=270 nM), does not display any significant binding to a large panel of biological targets and no significant inhibition of ion channels, enzymes and transporters that might be related to toxicity
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC10956 sPLA2-X inhibitor 31 sPLA2-X inhibitor 31 is a potent, selective secreted phospholipase A2 type X (sPLA2-X) with IC50 of 26 nM, displays 12-fold and 80-fold selectivity over sPLA2-Iia and sPLA2-V, respectively.
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