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SW076956

  Cat. No.:  DC10965   Featured
Chemical Structure
851717-83-4
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More than 5000 active chemicals with high quality for research!
Field of application
SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 851717-83-4
Chemical Name: N-(4-(5-(furan-2-yl)-1-(4-methylbenzoyl)-4,5-dihydro-1H-pyrazol-3-yl)phenyl)methanesulfonamide
Synonyms: SW-076956,SW 076956
SMILES: CS(NC1=CC=C(C2CC(C3=CC=CO3)N(C(=O)C3=CC=C(C)C=C3)N=2)C=C1)(=O)=O
Formula: C22H21N3O4S
M.Wt: 423.487
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
References: References 1. Chiang WC, et al. ACS Chem Biol. 2018 Jun 21. doi: 10.1021/acschembio.8b00421. View Related Products by Target Bcl-2
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
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DC5005 tw-37 TW-37 is a novel nonpeptide inhibitor to recombinant Bcl-2, Bcl-xL and Mcl-1 with Ki of 0.29 μM, 1.11 μM and 0.26 μM, respectively.
DC10965 SW076956 SW076956 is a small molecule that selectively disrupt Beclin 1/Bcl-2 binding as compared to Bax/Bcl-2 and Bim/Bcl-2 binding and induces autophagic flux at concentrations with minimal cytotoxicity.
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