Flavokawain B

  Cat. No.:  DC10972  
Chemical Structure
1775-97-9
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More than 5000 active chemicals with high quality for research!
Field of application
Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression.
Cas No.: 1775-97-9
Chemical Name: 2-Propen-1-one, 1-(2-hydroxy-4,6-dimethoxyphenyl)-3-phenyl-, (E)-
SMILES: C(C1=C(OC)C=C(OC)C=C1O)(=O)/C=C/C1=CC=CC=C1
Formula: C17H16O4
M.Wt: 284.311
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression; induces apoptosis in human myeloid leukemic cells by modifying NF-κB, possesses potential anti-inflammation and anti-cancer activities; also exhibits significant inhibition of the neurogenic nociceptive induced by intraplantar injections of glutamate and capsaicin in mice.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
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DC10972 Flavokawain B Flavokawain B is a natural chalcone that can induce apoptosis in androgen receptor-negative, hormone-refractory prostate cancer cell lines (IC50=3-50 uM), via up-regulation of death-receptor 5 and Bim expression.
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