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BAY-885

  Cat. No.:  DC10979   Featured
Chemical Structure
2307249-33-6
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More than 5000 active chemicals with high quality for research!
Field of application
BAY-885 is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM.
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 2307249-33-6
Chemical Name: (2-amino-4-(trifluoromethoxy)phenyl)(4-(7-(4-methylpiperazin-1-yl)pyrido[3,2-d]pyrimidin-4-yl)piperidin-1-yl)methanone
Synonyms: BAY885
SMILES: C(C1=CC=C(OC(F)(F)F)C=C1N)(N1CCC(C2N=CN=C3C=C(N4CCN(C)CC4)C=NC3=2)CC1)=O
Formula: C25H28F3N7O2
M.Wt: 515.541
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks4°C in DMSO,6 months-80°C in DMSO
Description: BAY-885 is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
Cat. No. Product name Field of application
DC10979 BAY-885 BAY-885 is a highly potent, selective ERK5 (MAPK7) inhibitor with IC50 of 40 nM.
DC7242 VX-11e(TCS ERK 11e) VX-11e is a potent, selective, and orally bioavailable inhibitor of ERK (Extracellular Signal-Regulated Kinase); antitumor agent.
DC8384 Sodium Tauroursodeoxycholate (TUDC) Sodium Tauroursodeoxycholate (TUDC) is a water soluble bile salt, used for the treatment of gallstones and liver cirrhosis.
DC7285 FR 180204 Selective ERK inhibitor (IC50 values are 0.14 and 0.31 μM for ERK2 and ERK1 respectively). Displays 30-fold selectivity for ERK over p38α (IC50 = 10 μM); displays no activity against human recombinant MEK1, MKK4, IKKα, PKCα, Src, Syc and PDGFα.
DC7283 SCH-772984 SCH772984 is a novel, specific inhibitor of ERK1/2 with IC50 of 4 nM and 1 nM, respectively.
DC10487 KO947 KO-947 is a small molecule inhibitor of extracellular-signal-regulated kinases 1 and 2 (ERK1/2), as a potential treatment for cancers in which the mitogen activated protein kinase (MAPK) pathway.
DC8866 DEL-22379 DEL-22379 is a water-soluble ERK dimerization inhibitor with IC50 of ∼0.5 μM.
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