Cas No.: | 27589-33-9 |
Chemical Name: | 2-chloro-5-(2H-tetrazol-5-yl)-4-(thiophen-2-ylmethylamino)benzenesulfonamide |
Synonyms: | Azosemidum |
SMILES: | C(S(N)(=O)=O)1=CC(C2=NNN=N2)=C(NCC2SC=CC=2)C=C1Cl |
Formula: | C12H11ClN6O2S2 |
M.Wt: | 370.83 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Azosemide (Azosemidum) is a potent Na-K-Cl Cotransporter NKCC1 with IC50 of 0.246 and 0.197 uM for hNKCC1A and NKCC1B, being about 4-times more potent than bumetanide; Azosemide is a high-ceiling loop diuretic agent used to treat hypertension, edema, and ascites. |