Umibecestat

  Cat. No.:  DC11105   Featured
Chemical Structure
1387560-01-1
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More than 5000 active chemicals with high quality for research!
Field of application
beta-secretase inhibitor.
Cas No.: 1387560-01-1
Chemical Name: N-{6-[(3R,6R)-5-amino-3,6-dimethyl-6-(trifluoromethyl)-3,6-dihydro-2H-1,4-oxazin-3-yl]-5-fluoropyridin-2-yl}-3-chloro-5-(trifluoromethyl)pyridine-2-carboxamide
SMILES: C(C(NC1=NC([C@@](C)2N=C(N)[C@@](C)(C(F)(F)F)OC2)=C(F)C=C1)=O)1=NC=C(C(F)(F)F)C=C1Cl
Formula: C19H15ClF7N5O2
M.Wt: 513.801
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: beta-secretase inhibitor
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC9901 Verubecestat (MK-8931) MK-8931 is a BACE1 inhibitor. MK-8931 binds significantly to β-secretase.
DC5053 LY2886721 LY2886721 is an BACE inhibitor used for the treatment of Alzheimer's Disease.
DC5180 LY2811376 LY2811376 is the first orally available non-peptidicβ-secretase(BACE1) inhibitor with IC50 of 239 nM-249 nM.
DC11551 Elenbecestat Elenbecestat (E2609) is a novel potent, oral BACE1 inhibitor for treatment of Alzheimer's disease..
DC11105 Umibecestat beta-secretase inhibitor.
DC8400 AZD3839 AZD3839 is a potent and selective BACE1 inhibitor with Ki of 26.1 nM, about 14-fold selectivity over BACE2. Phase 1.
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