CTDP-32476|CTDP32476

Cas No.:	928046-68-8
Chemical Name:	(R)-2-((R)-1-(4-chlorophenyl)-3-methylbutyl)piperidine hydrochloride
Synonyms:	CTDP32476
SMILES:	N1CCCC[C@H]1[C@H](C1=CC=C(Cl)C=C1)CC(C)C.[H]Cl
Formula:	C₁₆H₂₅Cl₂N
M.Wt:	302.283
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

CTDP-32476 is a potent and selective dopamine transporter (DAT) inhibitor and a competitive inhibitor of cocaine binding to the DAT with Ki of 12 nM; demonstrates 20-fold higher affinity for the DAT than cocaine, CTDP-32476 is more potent than methylphenidate in blocking [3H]-cocaine binding; Systemic administration of CTDP-32476 alone produced a slow-onset, long-lasting increase in extracellular nucleus accumbens DA, locomotion, and brain-stimulation reward, inhibited cocaine self-administration, cocaine-associated cue-induced relapse to drug seeking, and cocaine-enhanced extracellular DA in the nucleus accumbens.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
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DC5016	Vilazodone hydrochloride	Vilazodone (EMD 68843) is a combined serotonin specific reuptake inhibitor (SSRI) and 5-HT1A receptor partial agonist currently under clinical evaluation.
DC11242	SRI-31142	SRI-31142 (SRI31142) is a novel potent, putative allosteric dopamine transporter (DAT) inhibitor with Ki of 1.9 nM..
DC11110	CTDP-32476	CTDP-32476 is a potent and selective dopamine transporter (DAT) inhibitor and a competitive inhibitor of cocaine binding to the DAT with Ki of 12 nM.