DC Chemicals' products qualify for U.S. tariff exemptions. We guarantee no price increases due to customs duties and maintain stable supply, continuing to deliver reliable research solutions to our American clients.
| Cas No.: | 1202761-92-9 |
| Chemical Name: | 1-((1-(2-amino-5-chloropyrimidin-4-yl)indolin-6-yl)ethynyl)cyclopentan-1-ol |
| Synonyms: | AM0216 |
| SMILES: | C(C#CC1=CC2=C(C=C1)CCN2C1C(Cl)=CN=C(N)N=1)(O)1CCCC1 |
| Formula: | C19H19ClN4O |
| M.Wt: | 354.838 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | AM-0216 (Amgen16) is a highly potent inhibitor of NF-κB inducing Kinase (NIK) with Ki of 2 nM, selectively decrease viability of MMCLs in which NFkB activity is NIK-dependent; IKKβ inhibitor MLX and dexamethasone enhances cytotoxicity of NIK-inhibitors in MMCLs with NIK-dependent NFkB activation, blocks BAFF induced NFkB activation in myeloma cells combined with IKKβ inhibitors. |
MSDS
COA
| LOT NO. | DOWNLOAD |
|
|
|
| 2018-0101 |
|