| Cas No.: | 371217-32-2 |
| Chemical Name: | 6-{2-[2-methyl-1-(propan-2-yl)-1,2,3,4-tetrahydroisoquinolin-7-yl]cyclopropyl}naphthalene-2-carboximidamide |
| Synonyms: | A 317567 |
| SMILES: | C1=C2C(C=C(C3CC3C3=CC4=C(C=C3)CCN(C)C4C(C)C)C=C2)=CC=C1C(N)=N |
| Formula: | C27H31N3 |
| M.Wt: | 397.566 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A-317567 (A317567) is a novel potent acid sensing ion channel (ASIC) blocker with IC50 of 2-30 uM; inhibits pH 4.5-evoked ASIC currents, also equipotently blocks the sustained phase of ASIC3-like current; is more potent than amiloride in vitro and in vivo pain models, with minimal brain penetration. |
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| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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