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| Cas No.: | 2245887-38-9 |
| Chemical Name: | (S)-N-((S)-1-cyclohexyl-2-(3-morpholinopropanamido)ethyl)-3-(6-isopropylbenzo[d]thiazol-2-yl)-2-propionamidopropanamide |
| Synonyms: | DI591 |
| SMILES: | C(N[C@H](C1CCCCC1)CNC(=O)CCN1CCOCC1)(=O)[C@H](NC(=O)CC)CC1=NC2=CC=C(C(C)C)C=C2S1 |
| Formula: | C31H47N5O4S |
| M.Wt: | 585.808 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | DI-591 (DI591) is a potent, selective, cell-permeable inhibitor of the DCN1-UBC12 interaction with Ki of 10-12 nM for human DCN1 and DCN2; displays no affinity against DCN3/4/5 (Ki>10 uM); selectively inhibits neddylation of cullin 3 but has no or minimal effect on neddylation of other cullin family members; accumulates NRF2 protein and its transcriptional activation in cells. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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