Atogepant

  Cat. No.:  DC11514  
Chemical Structure
1374248-81-3
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More than 5000 active chemicals with high quality for research!
Field of application
A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine. Migraine.
Cas No.: 1374248-81-3
Chemical Name: (3'S)-N-[(3S,5S,6R)-6-methyl-2-oxo-1-(2,2,2-trifluoroethyl)-5-(2,3,6-trifluorophenyl)piperidin-3-yl]-2'-oxo-1',2',5,7-tetrahydrospiro[cyclopenta[b]pyridine-6,3'-pyrrolo[2,3-b]pyridine]-3-carboxamide
Synonyms: MK-8031;AGN-241689
SMILES: C12C[C@]3(C(=O)NC4=NC=CC=C43)CC1=CC(C(N[C@@H]1C[C@H](C3=C(F)C=CC(F)=C3F)[C@H](C)N(CC(F)(F)F)C1=O)=O)=CN=2
Formula: C29H23F6N5O3
M.Wt: 603.525
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine. Migraine
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC9398 MK-0974 MK-0974(Telcagepant) is a highly potent, selective, and orally bioavailable CGRP receptor antagonist with Ki values of 0.77 nM and 1.2 nM for human and rhesus CGRP receptors respectively; displays >1500-fold lower affinity for the canine and rat receptors
DC11514 Atogepant A potent, selective and orally available CGRP receptor antagonist for the prevention of migraine. Migraine.
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