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VHL-2

  Cat. No.:  DC11580  
Chemical Structure
1631137-31-9
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More than 5000 active chemicals with high quality for research!
Field of application
A VHL ligand for PROTAC..
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1631137-31-9
Chemical Name: (2S,4R)-1-((S)-2-((S)-2-acetamido-3-phenylpropanamido)-3,3-dimethylbutanoyl)-4-hydroxy-N-(4-(4-methylthiazol-5-yl)benzyl)pyrrolidine-2-carboxamide
Synonyms: VHL ligand 2
SMILES: N(C(=O)[C@H](NC(=O)[C@H](NC(=O)C)CC1=CC=CC=C1)C(C)(C)C)1C[C@@H](O)C[C@@H]1C(NCC1=CC=C(C2SC=NC=2C)C=C1)=O
Formula: C33H41N5O5S
M.Wt: 619.781
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A VHL ligand for PROTAC.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC47587 cIAP1 ligand 4 cIAP1 ligand 4 is a ligand for E3 ligase that can be used in the synthesis of PROTACs.
DC47586 (R)-Pomalidomide-pyrrolidine (R)-Pomalidomide-pyrrolidine, a CRBN ligand, can be connected to the ligand for protein by a linker to form PROTACs.
DC47217 Pomalidomide-7-NH2 Pomalidomide-7-NH2 is the Pomalidomide-based cereblon ligand used in the recruitment of CRBN protein. Pomalidomide-7-NH2 can be connected to the ligand for protein by a linker to form PROTACs.
DC47215 Thalidomide-4-C3-NH2 hydrochloride Thalidomide-4-C3-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-4-C3-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.
DC47208 Pomalidomide-5-OH Pomalidomide-5-OH (5-hydroxy pomalidomide) is the Pomalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein. Pomalidomide-5-OH can be connected to the ligand for protein by a linker to form PROTAC.
DC47206 Thalidomide-5-CH2-NH2 hydrochloride Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.
DC47143 Thalidomide-5-methyl Thalidomide-5-methyl is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
DC47142 Thalidomide-5-propoxyethanamine Thalidomide-5-propoxyethanamine is the Thalidomide-based cereblon (CRBN) ligand used in the recruitment of CRBN protein.
DC46963 Thalidomide-benzo Thalidomide-benzo hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-benzo can be connected to the ligand for protein by a linker to form PROTACs.
DC46962 Thalidomide-5-propargyne-NH2 hydrochloride Thalidomide-5-propargyne-NH2 hydrochloride is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-propargyne-NH2 hydrochloride can be connected to the ligand for protein by a linker to form PROTACs.
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