Cas No.: | 1332879-51-2 |
Chemical Name: | 2-(4-Aminobenzyl)-1,3-dioxo-2,3-dihydro-1H-benzo[de]isoquinoline-5-sulfonic acid sodium salt |
Synonyms: | Pitstop-1;Pitstop1 |
SMILES: | [Na+].C(=O)1C2=C3C(C=C(S([O-])(=O)=O)C=C3C(=O)N1CC1=CC=C(N)C=C1)=CC=C2 |
Formula: | C19H13N2NaO5S |
M.Wt: | 404.37 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A potent, selective inhibitor of clathrin-independent endocytosis with IC50 of 18 uM (inhibition of clathrin TD-amphiphysin B/C complex formation); inhibits endocytic recycling of synaptic vesicles in neurons and in situ. |