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| Cas No.: | 1419320-73-2 |
| Chemical Name: | (Z)-N-(5-(4-bromobenzylidene)-4-oxo-4,5-dihydrothiazol-2-yl)naphthalene-1-sulfonamide |
| Synonyms: | Pitstop-2;Pitstop2 |
| SMILES: | C(S(NC1=NC(=O)/C(=C/C2=CC=C(Br)C=C2)/S1)(=O)=O)1=C2C(C=CC=C2)=CC=C1 |
| Formula: | C20H13BrN2O3S2 |
| M.Wt: | 473.36 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | A small molecule inhibitor of clathrin terminal domain and inhibits clathrin-mediated endocytosis; inhibits endocytosis of transferrin receptor, a CDE cargo protein, but not affect endocytosis of shiga toxin; traps HeLa cells in metaphase through loss of mitotic spindle integrity and activation of the spindle assembly checkpoint, a useful tool for investigating clathrin spindle dynamics. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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