CK-2127107|CK-107;Reldesemtiv

Cas No.:	1345410-31-2
Chemical Name:	Reldesemtiv
Synonyms:	CK-2127107;Reldesemtiv;4S0HBYW6QE;Reldesemtiv (USAN);Reldesemtiv [USAN];1-[2-({[trans-3-Fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl]methyl}amino)pyrimidin-5-yl]-1H-pyrrole-3- carboxamide;DB15256;J3.610.548H;D11363;1-(2-(((Trans-3-fluoro-1-(3-fluoropyridin-2-yl)cyclobutyl)methyl)amino)pyrimidin-5-yl)-1H-pyrrole-3-carboxamide;1-[2-[[[3alpha-Fluoro-1beta-(3-fluoro-2-pyridyl)cyclobutane-1-yl]
SMILES:	FC1([H])C([H])([H])C(C2=C(C([H])=C([H])C([H])=N2)F)(C([H])([H])N([H])C2=NC([H])=C(C([H])=N2)N2C([H])=C([H])C(C(N([H])[H])=O)=C2[H])C1([H])[H]
Formula:	C₁₉H₁₈F₂N₆O
M.Wt:	384.3826
Purity:	>98%
Sotrage:	2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO

Description:

CK-2127107(CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM; has no effect on slow skeletal or cardiac myofibrils; significantly improves rotarod performance in exercise-intolerant LAD-HF rats.

MSDS

COA

LOT NO.	DOWNLOAD

2018-0101

Cat. No.	Product name	Field of application
DC12267	Verdiperstat (AZD3241)	Verdiperstat is a selective, irreversible and orally active myeloperoxidase inhibitor, with an IC50 of 630 nM, and is used in the research of neurodegenerative brain disorders.
DC11673	CK-2127107	CK-2127107(CK-107, Reldesemtiv) is a novel orally active fast skeletal troponin activator, selectively activates fast skeletal myofibrils with EC50 of 3.4 uM.