LY2922470
Cat. No.: DC11681
Chemical Structure
1423018-12-5
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Field of application
LY2922470 (LY-2922470) is a potent, selective, orally available GPR40 agonist with EC50 of 7 nM.
| Cas No.: |
1423018-12-5 |
| Chemical Name: |
(S)-3-(4-((5-((8-methoxy-3,4-dihydroquinolin-1(2H)-yl)methyl)thiophen-2-yl)methoxy)phenyl)hex-4-ynoic acid |
| Synonyms: |
LY-2922470;LY 2922470 |
| SMILES: |
C(O)(=O)C[C@H](C1=CC=C(OCC2SC(CN3C4=C(C=CC=C4OC)CCC3)=CC=2)C=C1)C#CC |
| Formula: |
C28H29NO4S |
| M.Wt: |
475.603 |
| Purity: |
>98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
LY2922470 (LY-2922470) is a potent, selective, orally available GPR40 agonist with EC50 of 7 nM; displays no activity against PPARα/β/γ (>10 uM); demonstrates potent, efficacious, and durable dose-dependent reductions in glucose levels along with significant increases in insulin and GLP-1 secretion in vivo. |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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