| Cas No.: | 1182129-77-6 |
| Chemical Name: | (2-(((3,5-dimethylisoxazol-4-yl)methyl)thio)phenyl)(4-(3-(trifluoromethyl)phenyl)piperazin-1-yl)methanone |
| Synonyms: | RU 302;RU302 |
| SMILES: | C(C1=CC=CC=C1SCC1=C(C)ON=C1C)(N1CCN(C2=CC=CC(C(F)(F)F)=C2)CC1)=O |
| Formula: | C24H24F3N3O2S |
| M.Wt: | 475.53 |
| Purity: | >98% |
| Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: | RU-302 is a small molecule pan-TAM inhibitor that targets the TAM Ig1-Gas6 interface, blocks Gas6-dependent TAM activation; effectively blocks Gas6-inducible Axl receptor activation with low micromolar IC50s; inhibits Gas6-inducible motility in Axl-expressing cell lines, and suppress H1299 lung cancer tumor growth in a mouse xenograft NOD-SCIDγ model. |
MSDS
COA
| LOT NO. | DOWNLOAD |
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| 2018-0101 |
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