GDC-0425

  Cat. No.:  DC11710  
Chemical Structure
1200129-48-1
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More than 5000 active chemicals with high quality for research!
Field of application
A potent, selective and orally active Chk1 inhibitor.
Cas No.: 1200129-48-1
Chemical Name: 5-((1-ethylpiperidin-4-yl)oxy)-9H-pyrrolo[2,3-b:5,4-c']dipyridine-6-carbonitrile
Synonyms: RG-7602;RG7602;GDC0425
SMILES: C12NC3C(C1=CC=CN=2)=C(OC1CCN(CC)CC1)C(C#N)=NC=3
Formula: C18H19N5O
M.Wt: 321.384
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A potent, selective and orally active Chk1 inhibitor; enhances gemcitabine efficacy in tumor xenograft models; shows greater chemopotentiation in cancer cell lines lacking p53 activity.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC11710 GDC-0425 A potent, selective and orally active Chk1 inhibitor.
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