Cas No.: | 1637573-02-4 |
Chemical Name: | (2R)-3-[4-(2-{4-[(2S)-3-chloro- 2-hydroxypropoxy]phenyl}propan-2-yl)phenoxy]propane- 1,2-diol acetate |
Synonyms: | EPI-506;EPI 506;EPI506 |
SMILES: | C(OC(=O)C)[C@H](O)COC1=CC=C(C(C2=CC=C(OC[C@@H](O)CCl)C=C2)(C)C)C=C1 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | A novel small-molecule inhibitor of androgen receptor (AR) N-terminal domain inhibitor for the treatment of advanced prostate cancer; AR NTD-targeting agents have the potential to overcome shortcomings of current hormonal therapies by inhibiting all forms of AR-mediated transcriptional activity, and as a result, may affect a broader AR population including mutational and splice variant ARs. |