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ME-344

  Cat. No.:  DC11929  
Chemical Structure
1374524-68-1
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More than 5000 active chemicals with high quality for research!
Field of application
A novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM.
Cas No.: 1374524-68-1
Chemical Name: (3R,4S)-3,4-bis(4-hydroxyphenyl)-8-methyl-3,4-dihydro-2H-chromen-7-ol
Synonyms: ME344;ME 344;NV-344
SMILES: C1OC2=C(C=CC(O)=C2C)[C@@H](C2=CC=C(O)C=C2)[C@H]1C1=CC=C(O)C=C1
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM; inhibits oxygen consumption rates, with specific effects on the respiratory chain, causes complex, redox-specific, and mitochondria-targeted effects in lung cancer cells; reduces tumor growth in OCI-AML2 xenograft model; an active metabolite of NV-128.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC11929 ME-344 A novel mitochondrial and mTOR inhibitor with potent anti-cancer activity, inhibits leukemia cell lines with IC50 of 70-260 nM.
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