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GPX-150

  Cat. No.:  DC11932  
Chemical Structure
236095-29-7
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More than 5000 active chemicals with high quality for research!
Field of application
A doxorubicin analog that demonstrates anti-cancer activity without cardiotoxicity, does not inhibit topoisomerase IIβ activity at 100 uM.
Cas No.: 236095-29-7
Chemical Name: (8R,10S)-10-(((2R,4S,5R,6S)-4-amino-5-hydroxy-6-methyltetrahydro-2H-pyran-2-yl)oxy)-6,8,11-trihydroxy-8-(2-hydroxyethyl)-12-imino-1-methoxy-7,9,10,12-tetrahydrotetracen-5(8H)-one
Synonyms: GPX 150;CNDO-101;DIDOX;5-imino-13-deoxy-doxorubicin
SMILES: C1=CC2C(=O)C3=C(O)C4C[C@](O)(CCO)C[C@@H](O[C@H]5O[C@H](C)[C@@H](O)[C@H](N)C5)C=4C(O)=C3C(=N)C=2C(OC)=C1
Purity: >98%
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Description: A doxorubicin analog that demonstrates anti-cancer activity without cardiotoxicity, does not inhibit topoisomerase IIβ activity at 100 uM
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
Cat. No. Product name Field of application
DC8923 AS-1413(Amonafide) Amonafide(AS1413) produces protein-associated DNA-strand breaks through a topoisomerase II-mediated reaction, but does not produce topoisomerase I-mediated DNA cleavage.
DC11932 GPX-150 A doxorubicin analog that demonstrates anti-cancer activity without cardiotoxicity, does not inhibit topoisomerase IIβ activity at 100 uM.
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