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Home > PROTACs > E3 Ligase Ligand

E3 ligase Ligand 1A

  Cat. No.:  DC22335   Featured
Chemical Structure
1948273-02-6
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More than 5000 active chemicals with high quality for research!
Field of application
E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer. (S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL)
Chemicals PropertiesBiological activity COA & MSDSRelated productsDatasheet
Cas No.: 1948273-02-6
Chemical Name: VHL ligand 2;(S,R,S)-AHPC-Me
Synonyms: VHL ligand 2;(S,R,S)-AHPC-Me
SMILES: N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O
Formula: C27H28N2O5S2
M.Wt: 444.59
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Publication: [1]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9.
Description: E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer.
MSDS
COA
LOT NO. DOWNLOAD
2018-0101
2018-0101
2018-0101
Cat. No. Product name Field of application
DC22337 E3 ligase Ligand 4(TC-E3 5032) E3 ligase Ligand 4 is a ligand of E3 ligase, used in PROTAC technology.
DC20512 VHL ligand 1 PROTAC-VHL-ligand is a von Hippel–Lindau (VHL) ligand used for the proteolysis targeting chimeras (PROTACs) method, induces target protein degradation..
DC22335 E3 ligase Ligand 1A E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer. (S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL)
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