E3 ligase Ligand 1A
Cat. No.: DC22335
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Chemical Structure
1948273-02-6
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Field of application
E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer.
(S,R,S)-AHPC-Me (VHL ligand 2) is the (S,R,S)-AHPC-based VHL ligand used in the recruitment of the von Hippel-Lindau (VHL)
| Cas No.: |
1948273-02-6 |
| Chemical Name: |
VHL ligand 2;(S,R,S)-AHPC-Me |
| Synonyms: |
VHL ligand 2;(S,R,S)-AHPC-Me |
| SMILES: |
N[C@@H](C(C)(C)C)C(N1[C@H](C(N[C@@H](C)C2=CC=C(C3=C(C)N=CS3)C=C2)=O)C[C@@H](O)C1)=O |
| Formula: |
C27H28N2O5S2 |
| M.Wt: |
444.59 |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Publication: |
[1]. Raina K, et al. PROTAC-induced BET protein degradation as a therapy for castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Jun 28;113(26):7124-9. |
| Description: |
E3 ligase Ligand 1A is a ligand of E3 ligase, used in PROTAC technology; E3 ligase Ligand 1A can be used in the research of cancer. |
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