Cas No.: | 167782-17-4 |
Chemical Name: | Methyl (2E,3E,5E,9E)-2-ethylidene-11-[(1R,5R)-4-hydroxy-4-methyl-2-oxo-6-oxa-3-azabicyclo[3.1.0]hexan-1-yl]-4,10-dimethyl-11-oxoundeca-3,5,9-trienoate |
Formula: | C21H27NO6 |
M.Wt: | 389.45 |
Purity: | >98% |
Sotrage: | 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
Description: | Epolactaene is a neuritogenic fungal isolate that arrests the cell cycle at the G0/G1 phase and induces the outgrowth of neurites in human neuroblastoma SH-SY5Y cells; inhibits DNA topoisomerase II (topo II), binds to Hsp60 Cys442 resulting in the inhibition of chaperone activity; also reacts with N-acetylcysteine methyl ester and induces the disulfide formation. |