DUN41875
Cat. No.: DC45585
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Chemical Structure
1295541-87-5
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Field of application
DUN41875, also known as SCD1 inhibitor-4, is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes. DUN41875 was first reported in Bioorgan.Med. Chem. Lett. (2011), 21(6), 1621-1625. This product has no formal name at the moment. For the convenience of communication, a temporal code name was therefore proposed according to MedKoo Chemical Nomenclature
| Cas No.: |
1295541-87-5 |
| Chemical Name: |
DUN41875 |
| SMILES: |
O=C(C1=C(C)N(CC2=CC=CC(C(F)(F)F)=C2)C=N1)NC3=NN(C)C=C3 |
| Formula: |
C17H16F3N5O |
| M.Wt: |
363.34 |
| Purity: |
>98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
DUN41875(SCD1 inhibitor-4) is a potent, orally active stearoylCoA desaturase-1 (SCD1) inhibitor. SCD1 inhibitor-4 can be used for the research of diabetes[1]. |
| Target: |
SCD1[1] |
| In Vivo: |
SCD1 inhibitor-4 (1~30 mg/kg) shows a dose-dependent decrease in desaturation index with a 55 % reduction at 1 mg/kg and 85% reduction at the 10 and 30 mg/kg doses[1]. |
| References: |
[1]. Atkinson KA, et al. N-benzylimidazole carboxamides as potent, orally active stearoylCoA desaturase-1 inhibitors. Bioorg Med Chem Lett. 2011;21(6):1621-1625. |
MSDS
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| MSDS_29312_DC45585_1295541-87-5 |
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