YTX-465
Cat. No.: DC12618
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Chemical Structure
2225824-53-1
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Field of application
YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD).
| Cas No.: |
2225824-53-1 |
| Chemical Name: |
N-(2-(4-(3-(1,3-dimethyl-1H-indazol-6-yl)-1,2,4-oxadiazol-5-yl)piperidin-1-yl)-2-oxoethyl)benzamide |
| Synonyms: |
YTX465;YTX 465 |
| SMILES: |
C(NCC(N1CCC(C2ON=C(C3=CC4=C(C=C3)C(C)=NN4C)N=2)CC1)=O)(=O)C1=CC=CC=C1 |
| Formula: |
C25H26N6O3 |
| M.Wt: |
458.522 |
| Purity: |
>98% |
| Sotrage: |
2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO |
| Description: |
YTX-465 (YTX465) is a specific small molecule that rescues yeast from a-Syn cytotoxicity with EC50 of 15 nM, via inhibiting Ole1, the yeast homolog of human stearoyl-CoA desaturase (SCD); YTX-465 is inactive at SCD1. |
| Target: |
SCD |
| References: |
References 1. Vincent BM, et al. Cell Rep. 2018 Dec 4;25(10):2742-2754.e31. View Related Products by Target Stearoyl-CoA Desaturase (SCD) |
MSDS
COA
| LOT NO. |
DOWNLOAD |
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| 2018-0101 |
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| 2018-0101 |
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