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Thalidomide-5-CH2-NH2 hydrochloride

  Cat. No.:  DC47206   Featured
Chemical Structure
1010100-22-7
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Field of application
Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.
Cas No.: 1010100-22-7
Chemical Name: 5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride
Synonyms: 5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione;5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)-2,3-dihydro-1H-isoindole-1,3-dione hydrochloride;5-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione hydrochloride;5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione hydrochloride;5-(aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindole-1,3-dione;hydrochloride;W15813;HY-W129872;Thalidomide-5-CH2-NH2 (hydrochloride);DA-68111;5-aminomethyl-2-(2,6-dioxo-piperidin-3-yl)-isoindole-1,3-dione hydrochloride;SCHEMBL1403707;Z3153424569;5-(Aminomethyl)-2-(2,6-dioxopiperidin-3-yl)isoindoline-1,3-dione HCl;1010100-22-7;EN300-27183929;AKOS040756415;ODZXEQVQLJKSQH-UHFFFAOYSA-N;Thalidomide-5-CH2-NH2 hydrochloride;CS-0187989;MFCD32666042
SMILES: O=C1C(CCC(N1)=O)N1C(C2C=CC(CN)=CC=2C1=O)=O
Formula: C14H13N3O4
M.Wt: 287.270723104477
Sotrage: 2 years -20°C Powder, 2 weeks 4°C in DMSO, 6 months -80°C in DMSO
Cat. No. Product name Field of application
DC47889 Thalidomide-5-NH2-CH2-COOH Thalidomide-5-NH2-CH2-COOH (compound 114) is a potent and selective inhibitor of tropomyosin receptor kinase (trk). Thalidomide-5-NH2-CH2-COOH is a ligand of E3 ligase. Thalidomide-5-NH2-CH2-COOH has the potential for the treatment of one or more diseases (extracted from patent WO2021170109A1) .
DC47206 Thalidomide-5-CH2-NH2 hydrochloride Thalidomide-5-CH2-NH2 (hydrochloride) is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-CH2-NH2 (hydrochloride) can be connected to the ligand for protein by a linker to form PROTACs.
DC46956 Thalidomide-5-COOH Thalidomide-5-COOH is the Thalidomide-based cereblon ligand used in the recruitment of CRBN protein. Thalidomide-5-COOH can be connected to the ligand for protein by a linker to form PROTACs.
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